A quieter relationship with food.
Weekly subcutaneous injection
Compounded semaglutide is a GLP-1 medication that supports appetite regulation. Through LuneRx, an independent licensed provider reviews your health history and determines whether a prescription is appropriate — it is never automatic.
Prescription required. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness, or quality. A licensed provider will determine whether treatment is appropriate for you.
What is compounded semaglutide?
Semaglutide is a GLP-1 receptor agonist — a long-acting version of a hormone your body already makes. It acts on receptors involved in appetite signaling, slows how quickly the stomach empties, and supports the body's insulin response, so meals stay satisfying longer.
Many people describe the qualitative effect as 'food noise' turning down — less of the constant low-grade pull toward food between meals. That quieter window is where new habits get room to take hold. Semaglutide has been clinically studied for weight management; individual results vary, and no outcome is guaranteed.
Compounded semaglutide is prepared by a state-licensed compounding pharmacy for an individual patient, pursuant to a prescription written by a licensed provider. Through LuneRx it is available only if the independent licensed provider who reviews your health history determines that treatment is appropriate.
How treatment works
Acts on GLP-1 receptors
Semaglutide works at the same receptors your body's own GLP-1 hormone uses — appetite centers in the brain, stomach motility, and the pancreas — supporting appetite regulation and a steadier response to meals.
Titrated gradually
If prescribed, treatment typically begins at a low dose that the reviewing provider increases gradually over time. Careful titration is how providers work to keep side effects manageable, and the schedule can slow or pause based on how you respond.
Reviewed as you go
Medication is one part of a supervised plan. Provider check-ins continue throughout treatment, and nutrition, movement, and sleep do the long-term work alongside the prescription.
What treatment involves, and what it is not
What treatment involves
- A required consultation reviewed by an independent licensed provider
- Gradual, monitored dose titration if treatment is prescribed
- Medication prepared and shipped by a state-licensed partner pharmacy
- Ongoing check-ins with the provider who knows your history
What it is not
- Not a guarantee of any outcome — individual results vary
- Not the same as, or a generic version of, any branded medication
- Not appropriate for everyone — sometimes the answer is no
- Not a substitute for changes in nutrition and activity
Important safety information
Compounded medications are prepared by a state-licensed compounding pharmacy for an individual patient pursuant to a licensed provider's prescription. They are not FDA-approved, and the FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Compounded medications are not the same as, and are not generic versions of, any FDA-approved medication.
Who should not use semaglutide
GLP-1 medications are generally not appropriate for people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), during pregnancy or breastfeeding, or with a history of pancreatitis, severe gastrointestinal disease, or significant kidney disease. This list is not exhaustive — the independent licensed provider who reviews your health history makes the final decision.
Common side effects
Nausea, constipation, fatigue, and heartburn are the most common, appearing most often during dose increases. Smaller meals, steady hydration, and a slower titration schedule all help, and the prescribing provider can adjust your plan if an effect persists.
Serious but rare risks
Pancreatitis, gallbladder problems, allergic reactions, and changes in vision for people with diabetic retinopathy are rare but real. Severe or persistent abdominal pain, vomiting that will not stop, yellowing of the skin or eyes, or a sudden change in vision are reasons to seek care promptly — not symptoms to wait out.
Drug interactions
Share every medication and supplement you take — prescription, over-the-counter, and herbal — during your consultation. Some combinations require closer screening or are not appropriate, including medications that lower blood sugar, which can interact with GLP-1 treatment. The reviewing provider evaluates your full profile before any prescription is written.
Pregnancy and breastfeeding
GLP-1 medications are not recommended during pregnancy, while breastfeeding, or while actively trying to conceive. If your circumstances change during treatment, tell the prescribing provider promptly.
If a side effect appears
Contact the prescribing provider first — many early side effects resolve with a dose adjustment or a change in schedule. For a severe allergic reaction, difficulty breathing, severe abdominal pain, or anything that feels like an emergency, call 911 or go to the nearest emergency room first.
Questions, answered.
No. Compounded semaglutide is not the same as, and is not a generic version of, Ozempic®, Wegovy®, or any other FDA-approved medication.
It is prepared by a state-licensed compounding pharmacy for an individual patient pursuant to a provider's prescription, and it is not FDA-approved — the FDA does not review compounded medications for safety, effectiveness, or quality.
No specific amount of weight loss can be promised, and individual results vary. Semaglutide has been clinically studied for weight management, and the provider who reviews your health history will discuss what a realistic course of treatment could look like for you.
Yes. Compounded semaglutide is a prescription medication, available only if an independent licensed provider determines that a prescription is appropriate after a required medical consultation. It is never dispensed without one.
Appetite typically returns as the medication leaves your system, which is one reason nutrition, movement, and sleep matter so much during treatment. If you are considering stopping, talk with the prescribing provider first — decisions about tapering, maintenance, or ending treatment are made together, not alone.
Eligibility is a medical decision made by an independent licensed provider after reviewing your health history — completing the assessment does not guarantee a prescription, and sometimes the honest answer is no. Services are not available in all states; see our States Served page for details.
You answer a short set of questions about your goals, health background, and lifestyle. An independent licensed provider reviews your answers and determines whether prescription treatment is appropriate for you. Our How It Works page walks through the full process.
Start with the prescribing provider — many early side effects settle with a dose adjustment or a slower schedule. Our Safety page covers common side effects, the rare serious ones, and how to report a problem.
Other treatments a provider may consider
- Weekly subcutaneous injection
Compounded Tirzepatide
A weekly injection that acts on both GIP and GLP-1 receptor pathways, considered case by case by the reviewing provider.
- Sublingual troche
Semaglutide Troche
A needle-free form of semaglutide that dissolves under the tongue, with lower systemic exposure than the weekly injection — an option a provider may consider where it fits.
- Weekly injection
MIC+B12 Injections
A supportive blend of methionine, inositol, choline, and vitamin B12 that a provider may add alongside a broader weight-loss plan — not a weight-loss medication on its own.
Prescription required. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness, or quality. A licensed provider will determine whether treatment is appropriate for you.
See if semaglutide is appropriate.
A two-minute assessment is the first step. An independent licensed provider reviews your health history and takes it from there.
Get StartedNo commitment required to complete the assessment.