A supporting role, never the lead.
Weekly injection
MIC+B12 pairs three lipotropic compounds with vitamin B12 as a supportive adjunct to a broader weight-loss plan. It is not a weight-loss medication, and the independent providers we work with do not position it as one.
Prescription required. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness, or quality. A licensed provider will determine whether treatment is appropriate for you.
What is MIC+B12?
MIC is a lipotropic blend — methionine, inositol, and choline, three compounds involved in how the liver processes fat and in the body's methylation chemistry. Paired with vitamin B12 (cyanocobalamin), it has been used for decades as an adjunct within medically supervised weight-loss care.
The honest framing matters: MIC+B12 is a supportive adjunct, not a weight-loss medication, and the independent providers we work with do not position it as a standalone weight-loss treatment. Where a provider includes it, it plays a supporting role alongside the things that carry a plan — nutrition, movement, sleep, and, where appropriate, prescription GLP-1 medication.
MIC+B12 injections are prepared by a state-licensed compounding pharmacy pursuant to a licensed provider's prescription. Like all compounded preparations, they are not FDA-approved.
How treatment works
Methionine, inositol, choline
These three compounds are involved in fat transport out of the liver and in methyl-group chemistry. Their role in a plan is nutritional support — they are cofactors, not appetite medications.
B12 as the energy floor
Vitamin B12 supports energy production and nerve function. Restoring a genuinely low B12 level can be felt; at normal levels the effect is typically modest. B12 is not a stimulant.
Added only where it fits
A provider may include MIC+B12 alongside a broader weight-loss plan — never as a standalone strategy. Whether it has a place in yours is the reviewing provider's judgment.
What it is, and what it is not
What it is
- A supportive nutritional adjunct
- A blend a provider may pair with a broader plan
- A source of B12 where levels are genuinely low
- A formula used in weight-loss care for decades
What it is not
- Not a weight-loss medication
- Not a substitute for GLP-1 treatment or lifestyle work
- Not a standalone weight-loss strategy
- Not a "fat burner" injection
Important safety information
Compounded medications are prepared by a state-licensed compounding pharmacy for an individual patient pursuant to a licensed provider's prescription. They are not FDA-approved, and the FDA does not review compounded medications for safety, effectiveness, or quality before they are dispensed. Compounded medications are not the same as, and are not generic versions of, any FDA-approved medication.
Who should not use MIC+B12
MIC+B12 is generally not appropriate for people with a known allergy to cobalt — vitamin B12 is a cobalt-containing molecule — or to any other component of the formulation, or for people with Leber's hereditary optic neuropathy. This list is not exhaustive; the reviewing provider makes the final decision.
Common side effects
Injection-site soreness, mild and short-lived flushing, and a harmless bright-yellow tint to the urine — excess water-soluble B vitamins being excreted — are the most common. Allergic reactions are rare but possible.
Drug interactions
Share every medication and supplement you take during your consultation, even for a supportive adjunct. The reviewing provider evaluates your full profile before anything is prescribed.
Pregnancy and breastfeeding
Discuss pregnancy, breastfeeding, or plans to conceive with the reviewing provider before starting any injectable therapy — and tell the prescribing provider promptly if your circumstances change.
Honest expectations
MIC+B12 is a modest adjunct, and presenting it as more than that would be a disservice. Where it appears in a plan, it is there to support the work that nutrition, movement, and — where prescribed — GLP-1 medication are doing.
If a side effect appears
Contact the prescribing provider first. For a severe allergic reaction, difficulty breathing, or anything that feels like an emergency, call 911 or go to the nearest emergency room first.
Questions, answered.
It is not positioned as a weight-loss treatment, because it is not one. MIC+B12 is a supportive adjunct. If your goal is meaningful weight loss, the conversation with the reviewing provider will center on a broader plan — and on whether prescription GLP-1 medication is appropriate for you.
If your B12 level is genuinely low, restoring it can make a felt difference. At normal levels the effect is typically modest — B12 is a vitamin, not a stimulant. Individual responses vary.
B vitamins are strongly colored, and what the body does not use is excreted in urine. The color change is harmless and expected.
That is a common way providers use it — as a supportive addition alongside prescription GLP-1 therapy. Whether the combination is appropriate for you is the reviewing provider's decision.
A prescription is required — MIC+B12 injections arranged through LuneRx are prepared by a state-licensed compounding pharmacy pursuant to a licensed provider's prescription, only after a provider determines they are appropriate for you. Compounded preparations are not FDA-approved, and the FDA does not review them for safety, effectiveness, or quality. They are not the same as, and are not generic versions of, any FDA-approved medication.
Eligibility is a decision made by an independent licensed provider after reviewing your health history — completing the assessment does not guarantee a prescription. Services are not available in all states; see our States Served page for details.
A short set of questions about your goals, health background, and lifestyle, reviewed by an independent licensed provider who determines what, if anything, is appropriate to prescribe. Our How It Works page walks through the full process.
Start with the prescribing provider. Our Safety page covers side effects, warning signs, and how to report a problem with any medication.
Other treatments a provider may consider
- Weekly subcutaneous injection
Compounded Semaglutide
A weekly GLP-1 injection that supports appetite regulation, available only when an independent licensed provider determines a prescription is appropriate.
- Weekly subcutaneous injection
Compounded Tirzepatide
A weekly injection that acts on both GIP and GLP-1 receptor pathways, considered case by case by the reviewing provider.
- Sublingual troche
Semaglutide Troche
A needle-free form of semaglutide that dissolves under the tongue, with lower systemic exposure than the weekly injection — an option a provider may consider where it fits.
Prescription required. Compounded medications are not approved or evaluated by the FDA for safety, effectiveness, or quality. A licensed provider will determine whether treatment is appropriate for you.
Support, framed honestly.
A two-minute assessment is the first step. An independent licensed provider determines whether MIC+B12 has a place in your plan.
Get StartedNo commitment required to complete the assessment.